Organic growers have a limited number of products they can use for control of insect pests. In this study, the OMRI-listed biological insecticide DiPel* DF was tested at two rates for efficacy in control of diamondback moth larvae in collards. A DiPel* only treatment program provided significant control of pest populations through the season. This study indicates that DiPel* can be an effective stand-alone insecticide for control of Lepidoptera pests.